What Is Monkeypox

Embark on a Quest with What Is Monkeypox

Step into a world where the focus is keenly set on What Is Monkeypox. Within the confines of this article, a tapestry of references to What Is Monkeypox awaits your exploration. If your pursuit involves unraveling the depths of What Is Monkeypox, you've arrived at the perfect destination.

Our narrative unfolds with a wealth of insights surrounding What Is Monkeypox. This is not just a standard article; it's a curated journey into the facets and intricacies of What Is Monkeypox. Whether you're thirsting for comprehensive knowledge or just a glimpse into the universe of What Is Monkeypox, this promises to be an enriching experience.

The spotlight is firmly on What Is Monkeypox, and as you navigate through the text on these digital pages, you'll discover an extensive array of information centered around What Is Monkeypox. This is more than mere information; it's an invitation to immerse yourself in the enthralling world of What Is Monkeypox.

So, if you're eager to satisfy your curiosity about What Is Monkeypox, your journey commences here. Let's embark together on a captivating odyssey through the myriad dimensions of What Is Monkeypox.

Showing posts sorted by date for query What Is Monkeypox. Sort by relevance Show all posts

What Is 'twee' And Why Is TikTok Debating Its Return?

What is 'twee' and why is TikTok debating its return?

What is 'twee' and why is TikTok debating its return?

In 2021, TikTok unseated Google as the most popular domain on the Internet, and now it's looking like it'll take over Instagram as the ultimate home for fashion influencers.

With one of the largest audiences on the planet, TikTok is responsible for the rise and fall of many a trend. When TikTok speaks, people listen. Lately, however, TikTok fashionistas have been divided over the potential resurgence of a very specific and iconic trend: twee.

@flashesofstyle How are we feeling about this resurgence? Idk yet 😅 #twee#tweestyle#tweefashion#fypシ#fyp♬ Why Do You Let Me Stay Here? - She & Him

Even if you're unfamiliar with the word, you'll likely recognize the look. Think early 2013 ModCloth aesthetic -- swooping bangs, Peter Pan collars, cutesy cardigans, skater skirts with patterned tights, red lipstick, ukuleles and typewriters.

Essentially, look at almost any image of Zooey Deschanel circa 2011-2014 to be smacked in the face with twee, or hipster fashion. It was an incredibly popular aesthetic, especially among the Tumblr crowd.

@steffydegref It's back, and I've been waiting forever. #twee#indie#indiesleaze#tumblr♬ Why Do You Let Me Stay Here? - She & Him

On the one hand, some users are adamant that the trend is returning, warning fashion followers to ready their ballet flats and berets. Others, however, are dismissing it as the latest in a line of TikTok algorithm bubbles destined to burn itself out on speculation and drama.

Regardless of whether it's back, though, it's already facing backlash. So why is an aesthetic causing so much division?

Here's the thing: It's not really about fashion at all. When you boil it down, the underlying issues of the debate aren't based on clothing choices. They're based on deceptive algorithms, negative online behavior and the fear of a cyclical internet.

The TikTok bubble effect

TikTok's algorithm is designed to know you better than you know yourself. It serves you endless customized videos that pay attention to your interactions, all to ensure you see the exact content you'll enjoy most.

But the funny thing about humans is that we actually have a very poor understanding of scale and relevance outside of our own bubbles. So, if you're getting inundated with a particular sound or trend on TikTok, your brain will likely think that it's a much bigger deal than it is.

Despite not having that many actual videos comparatively -- just under 7,000 for the main TikTok sound -- the twee revival debate is causing real-world trend forecasters to pay attention. Why? Because, as was the case when TikTok witches caused a real-world fuss by "hexing the moon," even microcosms and pockets of the internet have the capacity to create great social influence and change.

What's so scary about twee?

The initial wave of twee came at a time when Tumblr popularity was paramount -- the more reblogs you had on a cutesy photo with a poetic caption, the more indie and iconic you were. It was an attitude as much as a fashion movement, similar to what we'd now call hipsters.

Unfortunately, however, it also came with some deeply concerning attitudes toward body types and elitism.

@wannabehayleywilliams We still have time, audio still has less than 550 videos under it. #tumblr#2014tumblr#aesthetic#twee♬ Why Do You Let Me Stay Here? - She & Him

Between 2011 and 2014, Tumblr had itself a serious eating disorder and self harm problem, with countless blogs devoted to promoting and striving for anorexia and "thinspiration." Coinciding with the peak of twee popularity, the aesthetic went hand-in-hand with harmful "thinspo" propaganda – anyone who wasn't thin enough wasn't considered "twee" so much as "frumpy." It was elitist and dangerous.

As a result, the lingering perception of twee and indie sleaze for people who were on Tumblr in those days is often one of perilously thin legs clad in tights or sepia-toned cardigans covering self-harm scars.

We've learned a lot since the Tumblr days. We grew out of the mustache trend, we learned that Tom was the real villain in classic twee film (500) Days of Summer, but the Internet hasn't fully caught up with body neutrality and progress.

To this day, social media sites struggle to keep a lid on pro-anorexia content, with Instagram coming under fire for its failure to protect teens from that sort of content as recently as last month.

With TikTok already having faced similar issues, people noticing the resurgence of twee are concerned that, while we may dust off the cardigans and tights, we haven't come far enough to leave the harmful attitudes behind.

@rebxtat Maybe sharing a hot take whilst cleaning out my fish tank x #twee♬ Why Do You Let Me Stay Here? - She & Him

@vonmunster i looked like this and listened to chelsea grin #twee#indie#tumblr♬ Why Do You Let Me Stay Here? - She & Him

Do we need to worry about this?

As is so often the case online, the discourse surrounding the twee debate is bigger than the debate itself. What started as a simple trend revival has grown legs in part due to the attention that naysayers have brought upon it.

But as for whether we should be worried, it really comes down to how much faith people have in their own capacity to regulate content and how much they trust social media to keep the dangerous ideas at bay.

The concern is that if the negative associations with twee come back alongside the trend, there could be microcosms and TikTok algorithm bubbles circulating the same dangerous ideas and mentalities that caused such uproar on Tumblr.

In an article from The Guardian, it's suggested that TikTok could actually end up being more dangerous because of the demographic of its users. It's not hard to circumnavigate word restrictions -- we've already seen users get around TikTok censorship with intentional spelling mistakes -- and with so many young users it's a concern.

Sure, there may not be that many videos about it now, but for the people who live within that bubble, it feels big, and the power of teenage girl influence shouldn't be underestimated.

Let's just remember for a moment that nobody is arguing the merits of the actual clothes, though I'm sure nobody wants twee revival to venture into mustache-core again. Nobody is scared of a plaid skirt and tights combo.

But given the damage that the wider twee-thinspo Tumblr pairing did in the early 2010s, it's little wonder people are apprehensive.

Source

Here's Who Needs A Monkeypox Vaccine, And What We Know About It

Here's Who Needs a Monkeypox Vaccine, and What We Know About It

Here's Who Needs a Monkeypox Vaccine, and What We Know About It

What's happening

The monkeypox vaccine is available to people at higher risk of getting the disease, but supply has been limited. To stretch out more doses, the US is starting to administer the vaccine in a slightly different way that requires a smaller dose.

Why it matters

Vaccination is an important tool to slow the monkeypox outbreak happening in the US and other countries. Access to vaccines is crucial for people most at risk.

What it means for you

Some men who have sex with men are eligible for the vaccine, as are other people who may've been exposed to monkeypox.

The vaccine Jynneos is being given out a little differently now in some places. If you're eligible for a monkeypox vaccine, you might be getting a shot under a top layer of skin, instead of deeper into your arm. That's because the US Food and Drug Administration authorized intradermal injection for the monkeypox vaccine this month, which is an effort to increase the US supply of vaccine up to five times since intradermal injection requires a much smaller dose than one given subcutaneously.

Also called "dose-sparing," intradermal types of injections aren't new to health care. But the change in medical guidance on how the monkeypox vaccine can be administered reflects a shortage of Jynneos that's plagued the vaccine rollout since it began. Health officials have touted a national stockpile of vaccines that work against monkeypox as well as smallpox, but getting them out to states and into the arms of people who need them has been a challenge.

According to a report from The New York Times, a hurdle in the monkeypox vaccine rollout (besides limited supply of Jynneos) is that the federal system being used to move vaccines to states and cities is different from the system local health officials are used to, which is run by the US Centers for Disease Control and Prevention and is already linked to state databases. The current system states are using for the monkeypox vaccine is made for mass vaccine rollouts where every person would need a vaccine (like a smallpox bioterrorism event), and it's been difficult in some states for local health officials to track their orders or get to the site where the doses have been delivered, the Times reports.

But federal health officials are confident in the new intradermal vaccination method, which they say gives an immune response similar to that of the traditional method. But it still requires two doses, about 28 days apart. One-dose priority policies for the vaccine, which could potentially delay a second dose, have been put in place in cities like San Francisco and New York City, which make up a large portion of the country's monkeypox cases.

Here's what we know about monkeypox vaccination.

Read more: Monkeypox: What to Know About Variants, Symptoms and More

Who can get a monkeypox vaccine?

Exact criteria for who should get a monkeypox vaccine depend on the city or state people live in and how widespread the outbreak is there, but men who have sex with men and who have had multiple or anonymous sexual partners in the last two weeks are eligible in cities like New York. That's because gay and bisexual men are currently at higher risk in the outbreak, though anyone with close contact to monkeypox can get the disease. You may also be eligible if you were recently exposed to someone with monkeypox.

According to the CDC, you meet the criteria for a monkeypox vaccine if:

You're a contact of someone who has monkeypox or you were identified as possibly exposed via contact tracing.
You had a sexual partner within the last two weeks who has monkeypox.
You've had multiple sexual partners in the last two weeks in an area with a high number of monkeypox cases.
You are a lab or health care worker who's around orthopox viruses, including in animals.

If you think you qualify for a vaccine or were exposed to monkeypox, contact your local health department or doctor's office to find an appointment in your area. You can also book an appointment for the vaccine online, a process that'll walk you through the eligibility criteria. Here is New York City's vaccine appointment website. You can make an appointment and find a vaccine in San Francisco by calling one of the city's clinics or visiting its drop-in location.

An illustration showing the different types of vaccination methods — Colematt/Getty Images

What is intradermal vaccination?

Intradermal vaccination is a method that injects the vaccine under a more shallow layer of skin, typically on the inner side of the forearm. This should produce a "noticeable pale elevation of the skin," according to the US Centers for Disease Control and Prevention. Counties including Los Angeles county and Fulton county in Georgia (where Atlanta is) have already transitioned to intradermal injections, according to the White House.

Most vaccines we get these days go either into the muscle in our arm (intramuscular injection) or into the fatty tissue under our skin (subcutaneous injection), like Jynneos has been given so far. Subcutaneous injection of Jynneos is the only authorized method of vaccination for people younger than 18. If you get the monkeypox vaccine intradermally, you'll still need two doses.

When the FDA authorized the new vaccine method, the agency referenced a study published in 2015 that found that a smallpox vaccine given intradermally gave a similar immune response in people compared to the vaccine given subcutaneously.

What are the monkeypox vaccines?

The US has two vaccines in its national stockpile that work against monkeypox. Jynneos is currently being given out to people before an exposure, as well as after an exposure, as it's a newer vaccine that's safe for most people.

Jynneos (made by Bavarian Nordic) is a new-generation vaccine approved by the US Food and Drug Administration in 2019 for monkeypox and smallpox. It's a two-dose vaccine, with each shot given about four weeks apart. It uses a weakened virus and is approved for adults 18 and older who are at high risk of getting monkeypox or smallpox.

Because of limited supply, it's likely you'll only be able to book an appointment for the first dose for the time being. In New York City, for example, health officials say you'll be contacted if you received a first dose about the second dose in the coming weeks.

Side effects of Jynneos may include typical temporary vaccine side effects, including headache, chills and fatigue. There can also be some pain and swelling around the injection site, which can result in what some are reporting as a temporary swollen lump around the injection site.

ACAM2000 is a second-generation smallpox vaccine that also works against monkeypox. According to the CDC, ACAM2000 is a derivative of Dryvax, which helped eradicate smallpox. (The two diseases are closely related and both caused by orthopoxviruses, which makes this possible.) If necessary, the US Department of Health and Human Services said it's also prepared to ship out the ACAM2000 vaccine, which is in greater supply than Jynneos but remains a second choice in the monkeypox response because it has a side effect profile that isn't safe for certain people.

ACAM2000 is administered differently than the typical vaccine shot we're used to, including intradermal injection. It's given by dipping a needle into a vaccine solution which will then be "pricked" several times on the upper arm. It will cause a localized infection (a "pox"), prompting an immune response.

While ACAM2000 doesn't cause smallpox, it contains live vaccina virus, which isn't suitable for everyone. It could be unsafe for immunocompromised people, pregnant folks and those with certain heart or skin diseases, like eczema.

Smallpox was declared eliminated from the world in 1980. The US stopped routine vaccination against it in 1972, though some health care workers or people who work in labs may have had the vaccine. Historically, according to the CDC, smallpox vaccines were 95% effective against infection and protect you for about three to five years, and after that protection starts to wane.

Because of this, it's possible people born before the early 1970s who got the smallpox vaccine might have some cross-protective immunity against monkeypox, according to the WHO, but there is "little immunity" to younger people living in non-endemic countries because they've had no exposure to a similar virus.

Read more: Monkeypox: What Gay and Bisexual Men Need to Know

A smallpox vaccine scar. People born before the mid-1970s might have such a scar. Jynneos, a newer-generation monkeypox and smallpox vaccine, is not the same type of vaccine as the one used to eradicate smallpox and doesn't leave a scar.
Picture Alliance/Getty Images

How effective are the vaccines against monkeypox? How long do they take to work?

Giving Jynneos within four days of a monkeypox exposure is the best option for stopping the onset of the disease, according to the CDC. If it's given four to 14 days after an exposure, the CDC says, Jynneos may not prevent monkeypox but will likely reduce the severity of symptoms. However, this information was published when Jynneos was given only the "standard" way (subcutaneous injection).

The CDC says that the Jynneos vaccine takes two weeks (14 days) after the second dose for immunity to build, and that ACAM2000 takes four weeks for maximum immunity. Though many people are receiving only the first dose of Jynneos at this time, early research suggests that one dose will still offer some protection, at least for a shorter period of time.

Because the US outbreak of monkeypox is so new, there's no data yet on exactly how effective the vaccines will be in the current situation, according to the CDC.

You should still self-isolate if you develop symptoms of monkeypox after getting vaccinated, such as a rash.

A computer image of a monkeypox virus.
Uma Shankar Sharma/Getty Images

Why does the US have a stockpile of monkeypox vaccines?

The US has a stockpile of Jynneos and ACAM2000 on hand not because the country was worried about an outbreak of monkeypox (which has been endemic in some African countries for years), but in case smallpox becomes a public threat again. Smallpox was declared eliminated in the 1980s, and the last natural outbreak in the US happened in 1949. But smallpox is usually much more severe than monkeypox, and officials worry it could be used as biological warfare.

"The stockpile was created in the event of a biological weapons attack on the United States with smallpox," Dr. Amesh Adalja, an infectious-disease expert and senior scholar at the Johns Hopkins Center for Health Security said. In this event, health officials would not be rationing vaccines or using only the newer-generation vaccine, according to Adalja.

"If there was a smallpox attack, we would be using whatever vaccines we have to be able to deal with it," he added.

Why is there a monkeypox vaccine supply issue?

The supply of Jynneos, the newer vaccine specifically approved to prevent monkeypox, has been in particularly short supply.

Officials who spoke to The New York Times said the supply issue is partly because the government waited too long to ask Bavarian Nordic, which makes Jynneos, to bottle and fill the vaccine order the US had already purchased.

Another report by the Times alleges that the US national stockpile of monkeypox and smallpox vaccines dwindled because the government never replaced the expired doses and instead put money into technology that would extend their shelf life. Part of the reason for this was that the government created the stockpile not for monkeypox but for smallpox, which is a more contagious and often more serious disease officials fear could be used in biological warfare against the US.

The US Department of Health and Human Services didn't respond to a request for comment on the reports.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Source

Here's Who Needs A Monkeypox Vaccine, And What We Know About It

Who can get monkeypox vaccine can i get a monkeypox vaccine the one who needs you here s who i am camp here s how here s hopin instrumental here sdk here string powershell

Here's Who Needs a Monkeypox Vaccine, and What We Know About It